Nmr studies in solution of poly-L-proline
نویسندگان
چکیده
منابع مشابه
Elucidation of the poly-L-proline binding site in Acanthamoeba profilin I by NMR spectroscopy.
The multifunctional protein profilin is one of the most abundant proteins in the cytoplasm and is thought to regulate actin assembly and the phosphoinositide signaling pathway. Profilin binds to several different ligands including actin, poly-L-proline, and the head groups of polyphosphoinositides. Knowledge of profilin/ligand interactions is important for understanding the physiology of profil...
متن کاملRedetermination of poly[μ-chlorido-heptachlorido-μ3-l-proline-μ2-l-proline-tetramercury(II)]
The asymmetric unit of the title compound, [Hg(4)Cl(8)(C(5)H(9)NO(2))(2)](n), consists of four HgCl(2) units and two L-proline ligands in the zwitterionic form. In each HgCl(2) unit, the Hg(II) ion is strongly bonded to two Cl atoms, and the Hg(II) ions in two of the HgCl(2) units are chelated by O atoms of two l-proline ligands, with one strong and one weak Hg-O bond. In the crystal structure,...
متن کاملNMR crystallography of α-poly(L-lactide).
A complementary approach that combines NMR measurements, analysis of X-ray and neutron powder diffraction data and advanced quantum mechanical calculations was employed to study the α-polymorph of L-polylactide. Such a strategy, which is known as NMR crystallography, to the best of our knowledge, is used here for the first time for the fine refinement of the crystal structure of a synthetic pol...
متن کاملConformations and Mutarotations of Poly(5-methyl-l-proline)
Optically active poly(cis-5-methyl-L-proline) and poly(trans-5-methyl-L-proline) were synthesized from their respective N-carboxy-anhydrides (NCA). Analysis of the i.r., u.v., n.m.r., ORD, and CD spectra of the polymers showed that two different conformations of each polymer exist in the solid and in solution in appropriate solvents. Form I and form II of poly(trans-5-methylL-proline) were foun...
متن کاملPolymers of tripeptides as collagen models. IV. Structure analysis of poly(L-proly-glycyl-L-proline).
Poly(L-prolyl-glycyl-L-proline) closely resembles collagen in its X-ray diffraction pattern, which indicates that it has a triple-helical structure with the same helical parameters as the protein. A detailed conformational analysis has been made of the polytripeptide. A computer was used systematically to generate structures having the observed helical parameters, as well as standard bond lengt...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biopolymers
سال: 1969
ISSN: 0006-3525,1097-0282
DOI: 10.1002/bip.1969.360080218